Degeneration is not time dependent. There’s even been traces of osteoarthritis in Neanderthals. “Wear and tear” are also not limited to humans. It predominantly occurs in vertebrates like birds, fish and mammals. Except for bats and sloths, which hang upside down most of their lives, with little weight bearing on their joints. It is unclear why some people are more prone to develop osteoarthritis than others.
Osteoarthritis presents mainly in people over the age of 70, but degeneration of the cartilage often starts as soon as the age of 35. Osteoarthritis is about equally as common in men and women. In addition, genetics play a role.
Sufficient exercise is extremely beneficial. The opposite, namely rest, often negatively impacts the joints. The aim is to keep the joints mobile and moving as this improves lubrication. Increased weight bearing and obesity can also increase the chance of osteoarthritis.